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Eye Care Combigan (Generic) Generic drugs, marketed without brand names, contain the exact same active ingredients used in their brand-name counterparts, but cost significantly less. The drugs are required to meet US Food and Drug Administration (FDA) standards for safety, purity and effectiveness.

Combigan Ophthalmic Solution is a prescription medicine used for the treatment of pressure in the eyes (ocular hypertension) and glaucoma. It works by decreasing the pressure of fluid in the eye (aqueous humor), which helps in lowering the increased eye pressure.


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Ophthalmic solution containing brimonidine and timolol What exactly is an ophthalmic solution of brimonidine and timolol? Brimonidine lowers the quantity of fluid that is present in the eye, which in turn lowers the pressure that is present within the eye. Timolol is a beta-blocker that also lowers the pressure within the eye. It does both of these things. To treat open-angle glaucoma or ocular hypertension, brimonidine plus timolol ophthalmic (for the eyes) is a medication that is used topically (high pressure inside the eye). Warnings If you have a history of asthma or chronic obstructive pulmonary disease (COPD), or if you have a serious heart condition such as "AV block," severe heart failure, or slow heartbeats that have caused you to faint in the past, you should not use brimonidine and timolol ophthalmic. These medications should be avoided at all costs. It is not recommended to administer brimonidine and timolol ophthalmic to a child who is younger than 2 years old. Before beginning to use this medication If you have an allergy to brimonidine and timolol ophthalmic, or if you have a history of asthma or chronic obstructive pulmonary disease (COPD), or if you have a serious heart condition such as "AV block," severe heart failure, or slow heartbeats that have caused you to faint in the past, you should not use this medication. Tell your doctor if you have any of the following conditions before using brimonidine and timolol ophthalmic: congestive heart failure; coronary artery disease; a history of stroke or blood clot; high or low blood pressure; circulation problems (such as Raynaud's syndrome); depression; diabetes (using brimonidine and timolol ophthalmic may make it harder for you to tell when you have low blood sugar); a thyroid disorder; any FDA pregnancy category C. Brimonidine and timolol ophthalmic might potentially cause damage to an unborn child; however, this is not yet established. When you are taking this medicine, you should inform your doctor if you are pregnant or if you intend to become pregnant in the near future. Timolol ophthalmic has been shown to enter breast milk, where it might potentially affect a breastfeeding infant. When you are using brimonidine and timolol ophthalmic, you should not breastfeed your child. Under no circumstances should you administer this medication to a youngster before seeing a physician. How should I administer the ophthalmic combination of brimonidine and timolol? Always make sure to follow all of the instructions on the label of your medication. This drug should not be used in bigger or lesser dosages, nor should it be taken for a longer period of time than is indicated. It is not safe to use this medicine if you are also going to be wearing contact lenses. Brimonidine and timolol ophthalmic may include a preservative that can cause soft contact lenses to turn a yellowish tint if they are used for an extended period of time. After administering this medication, you should refrain from putting your contact lenses in for at least 15 minutes. Before using the eye drops, you should wash your hands. To administer the eye drops, tilt your head back slightly and pull down on your lower eyelid to form a little pocket. Next, place the dropper inside the pocket. Keep the tip of the dropper pointed away from the eye as you hold it. Turn your head away from the bottle as you squeeze out a drop by looking upward. Put your head down and close your eyes for two or three minutes without blinking or squinting. Keep your eyes closed. To prevent the liquid from flowing into your tear duct, place the tip of your finger on the inside corner of your eye and gently push there for approximately one minute. Take only the amount of drops that have been recommended by your healthcare provider. Wait approximately five minutes in between each drop if you are using more than one. Before applying any additional eye drops that your doctor has ordered, you should wait at least ten minutes. It is important not to get the tip of the eye dropper wet or to put it in contact with your eye. Your eye can become infected if you use a dropper that has been contaminated, which might result in significant visual difficulties. Eye drops should not be used if the liquid has changed color or if there are particles present in the bottle. Make a new drug appointment with your pharmacist. If you have any kind of eye injury or infection, as well as if you need to have any kind of surgery, especially eye surgery, you should contact your doctor as soon as possible. Keep at room temperature and away from heat and moisture when storing. Do not freeze. While not in use, ensure that the cap is securely fastened on the bottle. What should I try to steer clear of while I'm under the influence of brimonidine and timolol ophthalmic? It's possible that this drug will affect either your thoughts or your reactions. While you are driving or engaging in any activity that needs you to be aware, exercise extreme caution. If your doctor has not given you specific instructions to do so, you should not take any additional eye drugs. Side effects of brimonidine and timolol in ophthalmic solution You should seek immediate medical attention if you experience any of the following symptoms of an allergic reaction: hives, difficulty breathing, and swelling of the face, lips, tongue, or neck are all symptoms of anaphylaxis. Brimonidine with timolol ophthalmic may induce severe adverse reactions in certain people. If you have a slow or uneven heart rate; pounding heartbeats or fluttering in your chest; shallow breathing; the feeling that you might pass out; severe swelling, redness, or discomfort in or around your eye; eye pain or increased watering; or numbness or tingly feeling in your hands or feet, you should contact your doctor as soon as possible. It is possible that brimonidine and timolol ophthalmic will cause you to feel drowsy or fatigued; your eyes may become somewhat itchy, red, or irritated; and administering the eye drops may cause you to have a little stinging or burning sensation. What other medications might potentially interact negatively with brimonidine and timolol ophthalmic? When used with other medications that make you sleepy or slow your breathing, the effects of brimonidine and timolol ophthalmic can become much more pronounced. Before taking brimonidine and timolol ophthalmic in conjunction with a sleeping pill, narcotic pain drug, muscle relaxer, or medication for anxiety, depression, or seizures, you should see your physician. Tell your doctor about any and all medications you take, including those you begin or stop taking while you are receiving treatment with brimonidine and timolol ophthalmic, particularly: digoxin, digitalis; reserpine; an antidepressant such as amitriptyline, bupropion, clomipramine, desipramine, doxepin, duloxetine, fluoxetine, imipramine, nortriptyline, paroxetine This list does not contain everything. There is a possibility that brimonidine and timolol ophthalmic will interact negatively with other medications, such as prescription and over-the-counter pharmaceuticals, vitamins, and herbal supplements. This drug guide does not provide a description of all potentially harmful interactions.


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