Cardiovascular DiseasesEdarbyclor (Generic)
Generic drugs, marketed without brand names, contain the exact same active ingredients used in their brand-name counterparts, but cost significantly less. The drugs are required to meet US Food and Drug Administration (FDA) standards for safety, purity and effectiveness.
Edarbyclor
Edarbyclor, also known as azilsartan medoxomil/chlorthalidone, is a prescription medication that combines the effects of two different medications into a single tablet. The medications complement one another in their ability to treat individuals who suffer from high blood pressure, often known as hypertension.
Azilsartan is an angiotensin II receptor blocker (sometimes called an ARB). Chlorthalidone is a thiazide diuretic (water pill).
Azilsartan and chlorthalidone is a combination medicine used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.
Azilsartan and chlorthalidone may also be used for purposes not listed in this medication guide.
Warnings
You should not use azilsartan and chlorthalidone if you are unable to urinate.
Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Ask your doctor about a blood pressure medication that is safer to use during pregnancy.
If you have diabetes, do not use azilsartan and chlorthalidone together with any medication that contains aliskiren (a blood pressure medicine).
Before taking this medicine
You should not use this medicine if you are allergic to azilsartan or chlorthalidone, or if you are unable to urinate.
If you have diabetes, do not use azilsartan and chlorthalidone together with any medication that contains aliskiren (a blood pressure medicine).
You may also need to avoid taking azilsartan and chlorthalidone with aliskiren if you have kidney disease.
Tell your doctor if you have ever had:
liver or kidney disease;
gout;
an electrolyte imbalance (such as low levels of potassium in your blood);
heart disease or a stroke; or
if you are dehydrated.
Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.
Azilsartan and chlorthalidone can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). Ask your doctor about a blood pressure medication that is safer to use during pregnancy.
You should not breastfeed while you are using this medicine.
Azilsartan and chlorthalidone is not approved for use by anyone younger than 18 years old.
How should I take azilsartan and chlorthalidone?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take azilsartan and chlorthalidone with or without food.
Your blood pressure will need to be checked often. Your kidney function may also need to be checked.
You may have very low blood pressure while taking this medicine. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual.
Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.
Store in the original container at room temperature, away from moisture, heat, and light.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What should I avoid while taking azilsartan and chlorthalidone?
Do not use potassium supplements or salt substitutes, unless your doctor has told you to.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
Azilsartan and chlorthalidone side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
feeling like you might pass out;
little or no urination;
swelling, weight gain, feeling short of breath; or
signs of electrolyte imbalance--dry mouth, extreme thirst, weakness, drowsiness, restless feeling, confusion, increased or decreased urination, nausea and vomiting, constipation, muscle pain or weakness, fast heart rate, or seizure (convulsions).
Common side effects may include:
dizziness; or
feeling tired.
This is not a complete list of side effects and others may occur.
What other drugs will affect azilsartan and chlorthalidone?
Tell your doctor about all your other medicines, especially:
digoxin;
lithium;
a diuretic or "water pill"; or
other heart or blood pressure medicines.
This list is not complete. Other drugs may affect azilsartan and chlorthalidone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
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