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Tolvaptan tablets Tolvaptan: what exactly is it? Tolvaptan works by lowering the body's overall production of a hormone that controls the proportion of water to salt (sodium) in the blood. When this hormone is present in high concentrations, it can lead to an imbalance, which in turn can induce low sodium levels and fluid retention. Tolvaptan is prescribed to patients with heart failure in order to treat hyponatremia, which is characterized by abnormally low amounts of salt in the blood, as well as certain hormonal abnormalities. Tolvaptan increases the flow of urine without producing an excessive loss of salt from the body as a result of urination. In addition to the uses that are described in this pharmaceutical guide, tolvaptan may also be utilized for other purposes. Information That Is Vital Whenever you begin or resume treatment with tolvaptan, you will be required to do so while under the supervision of a medical professional in a hospital setting. Talk to your primary care physician about all of the medications you are currently taking, as well as any new ones or ones you discontinue taking. There are many medications that can interact with one another, and certain drugs should never be used together. Notify your caregivers immediately if you have any of the following symptoms, which may indicate that your hyponatremia is being treated too rapidly: issues with speech or muscle control, difficulty swallowing, difficulty moving your arms and legs, disorientation, or seizures. If you are taking tolvaptan at home and notice any symptoms of liver trouble, including a loss of appetite, upper stomach pain, dark urine, or jaundice, you should contact your doctor immediately (yellowing of the skin or eyes). Before beginning to use this medication You should not take tolvaptan if you are allergic to it, or if you have autosomal dominant polycystic kidney disease, or if you are unable to urinate, or if you are unable to tell when you are thirsty, or if you are severely dehydrated and feel like you might pass out, or if you are unable to tell when you are severely dehydrated and feel like you might pass out (unless you receive tolvaptan through a special program that includes frequent liver function tests). When combined with other medications, certain drugs might have side effects that are undesirable or even deadly. If you are also taking nefazodone, an antibiotic (such as clarithromycin or telithromycin), antifungal medicine (such as itraconazole or ketoconazole), or medication for HIV/AIDS (such as indinavir, nelfinavir, ritonavir, or saquinavir), your doctor may alter your treatment plan. Inform your physician if any of the following apply to you: you have kidney disease or problems with urination; you have liver disease (especially cirrhosis); you are also taking desmopressin (dDAVP), or a diuretic or "water pill;" you are malnourished; or you have been drinking large amounts of alcohol. There is insufficient evidence to determine whether or not tolvaptan poses a risk to an unborn child. Inform your doctor if you are pregnant. When using this medication, it is possible that breastfeeding will not be a healthy option. Talk to your physician about any potential dangers. What is the recommended dosage of tolvaptan? In the event that you have any severe adverse effects, your initial dosage will be administered in a medical facility or clinic. Read all of the medication guides or instruction papers that come with your medicine, and make sure to follow all of the guidelines that are included on the prescription label. Always follow the directions on the label while taking medication. Use of tolvaptan for an extended period of time might result in severe liver damage or even death. Tolvaptan treatment should not be continued for more than 30 days. Tolvaptan can be taken either with food or on an empty stomach. This medication should be taken together with a full glass (eight ounces) of water. Within the first twenty-four hours after taking tolvaptan, it is important to consume a large amount of fluids but to steer clear of alcoholic beverages. When being treated for hyponatremia, you should make sure to consume the types and amounts of liquids that have been prescribed to you by your physician. Make an appointment with your primary care physician if you experience persistent nausea or diarrhea, or if you are sweating more than normal. While taking this drug, it is easy to get dehydrated, which can lead to a host of unpleasant and even dangerous adverse effects. You will need to undergo medical examinations on a regular basis. Keep at room temperature and away from heat and moisture when storing. Do not resume taking tolvaptan at home if you have stopped taking it for any period of time, regardless of how long the break was. Whenever you begin or resume treatment with tolvaptan, you will be required to do so while under the supervision of a medical professional in a hospital setting. What can I expect if I forget to take a dose? You should take the medication as soon as it is convenient for you to do so, but you should omit the missed dose if it is almost time for your next scheduled dosage. It is not recommended to take two dosages at once. While I am under the influence of tolvaptan, what should I try not to do? Steer clear of alcoholic beverages. Tolvaptan may cause undesirable side effects due to a potential interaction with grapefruit, which may occur. Grapefruit products should be avoided at all costs. Tolvaptan side effects You should seek immediate medical attention if you have the following symptoms of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or neck. Notify your caregivers right once if you have any of the following symptoms, since they may indicate that your hyponatremia is being treated too quickly: issues with speech or muscular control; difficulty swallowing; difficulty moving arms and legs; disorientation; changes in mood; or a seizure might be symptoms of a stroke. While taking tolvaptan at home, call your doctor at once if you have:\sweakness, or a light-headed feeling (like you might pass out);\sliver problems�right-sided upper stomach pain, vomiting, loss of appetite, yellowing of your skin or eyes, not feeling well; or\sdehydration symptoms�feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin.