Hepcinat® LP

Tablet containing Ledipasvir and Sofosbuvir What exactly are the medications ledipasvir and sofosbuvir? Both ledipasvir and sofosbuvir are examples of antiviral drugs that stop the hepatitis C virus, often known as HCV, from replicating in your body. A combination medication called ledipasvir and sofosbuvir is used to treat patients with hepatitis C who have the genotypes 1, 4, 5, or 6. This medication may be administered to adults and children over the age of 12 who weigh at least 77 pounds or who are at least 12 years old (35 kilograms). In rare cases, the combination of ledipasvir and sofosbuvir is administered in conjunction with a different medication known as ribavirin. In addition to the uses described in this drug guide, ledipasvir and sofosbuvir may also be utilized for other purposes. In regards to ledipasvir and sofosbuvir, what is the most crucial piece of information that I need to be aware of? If you are already taking sofosbuvir pills, you should not use ledipasvir and sofosbuvir at the same time (Sovaldi). Ledipasvir and sofosbuvir pose a risk of reactivating or aggravating an existing case of hepatitis B in patients who have a history of the virus. In order to monitor your liver function accurately, you will require periodic blood tests. Before beginning treatment with ledipasvir and sofosbuvir, what questions should I ask my healthcare provider? If you have an allergy to ledipasvir and sofosbuvir or if you are already taking sofosbuvir pills, you should not take ledipasvir and sofosbuvir (Sovaldi). Tell your doctor if you have a history of hepatitis B; liver problems other than hepatitis; a history of liver transplant; kidney disease (or if you are on dialysis); HIV or AIDS; or a heart rhythm problem for which you take a medicine called amiodarone. This will ensure that ledipasvir and sofosbuvir is safe for you to take (Cordarone, Pacerone). If you have severe kidney disease; a hemoglobin blood cell disorder such as sickle-cell anemia or thalassemia; if you are pregnant; or if you are a man and your sexual partner is pregnant, you should not use ledipasvir and sofosbuvir in combination with ribavirin. These conditions call for a different course of treatment. It is not anticipated that ledipasvir and sofosbuvir would cause any damage to an unborn child. Inform your physician if you are pregnant or if you want to become pregnant in the near future. It is possible to combine the antiviral drugs ledipasvir and sofosbuvir with still another medication known as ribavirin. Ribavirin exposes an unborn child to a risk of birth abnormalities as well as possible death. Before beginning therapy with ribavirin, you will likely need to demonstrate that you are not pregnant by passing a pregnancy test each month. Ribavirin should not be used by pregnant women, regardless of whether they are men or women. If you are a guy and your sexual partner is pregnant, you should avoid taking ribavirin at all costs. If a man is the father of an unborn kid while he is taking ribavirin, there is a possibility that the unborn child will be injured. Employ at least two methods of contraception that are shown to be effective in order to avoid becoming pregnant while either sexual partner is on ribavirin. When your treatment is over, you should continue to use two different methods of birth control for at least another six months. Notify your healthcare provider as soon as possible if you become pregnant while either you or the potential father is taking ribavirin. What is the recommended dosage for ledipasvir and sofosbuvir? Your physician will examine the results of your blood tests to determine whether or not you have any problems that might prevent you from using ledipasvir and sofosbuvir in a safe manner. Always make sure to follow all of the instructions on the label of your medication. Do not use this medication in greater or lower doses than indicated, nor for a longer period of time than specified. Both ledipasvir and sofosbuvir can be taken with or without food depending on your preference. Always remember to take your medication at the same time each day. The combination of ledipasvir and sofosbuvir is typically administered once daily for a period ranging from 12 to 24 weeks. Always adhere to the dose directions provided by your physician. In order to monitor your liver function accurately, you will require periodic blood tests. Combinations of medications are frequently used in the treatment of hepatitis C. Always follow your physician's instructions while using any medicine. You should go through and read all of the patient information, prescription guidelines, and instruction sheets that have been sent to you. Do not make any adjustments to your dosage or drug regimen without first consulting your doctor. Any individual who has chronic hepatitis C should continue to receive treatment from a medical professional. It is not recommended that you discontinue the use of ledipasvir and sofosbuvir all of a sudden. Your illness may become more difficult to manage with hepatitis C antiviral medication if you suddenly stop using the drug. Ledipasvir and sofosbuvir pose a risk of reactivating or aggravating an existing case of hepatitis B in patients who have a history of the virus. Over the course of therapy, as well as for many months after you have stopped taking this medication, you will be required to have tests done to evaluate your liver's function. Keep this medication in its original container at room temperature, away from moisture and heat, and out of the reach of children. What can I expect if I forget to take a dose? When you realize you missed a dosage, take it as soon as you can. If it is almost time for your next scheduled dosage, you should skip the dose that you missed. It is not necessary to take additional medication in order to make up for a missed dosage. While I am taking ledipasvir and sofosbuvir, what should I try to stay away from? If you take ledipasvir with sofosbuvir, you shouldn't take an antacid within four hours before or after taking the medication. Antacids, in particular those containing aluminum or magnesium, fall into this category (Acid Gone, Aldroxicon, Alternagel, Di-Gel, Gaviscon, Gelusil, Genaton, Maalox, Maldroxal, Milk of Magnesia, Mintox, Mylagen, Mylanta, Pepcid Complete, Rolaids, Rulox, and others). Using the antiviral medications ledipasvir and sofosbuvir won't stop you from transmitting hepatitis C to other individuals. Do not engage in unprotected sexual activity, nor should you share utensils such as razors or toothbrushes. Have a conversation with your healthcare provider about effective methods of preventing the spread of HCV through sexual activity. It is never safe, even for a healthy individual, to share needles that have been used for drugs or medicine. The adverse effects of ledipasvir and sofosbuvir You should seek immediate medical attention if you have the following symptoms of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or neck. If you also take a medication for your heart called amiodarone, you should contact your physician as soon as possible if you experience any of the following symptoms: extreme fatigue; unusual weakness; a general feeling of illness; confusion or memory problems; a lightheaded feeling, as though you might pass out; slowed breathing; feeling short of breath; chest pain; slow heartbeats; or a weak pulse. Weakness, headaches, and a sensation of exhaustion are examples of common adverse effects. Which other medications might potentially interact with ledipasvir and sofosbuvir? There are many different medicines that have the potential to interact with ledipasvir and sofosbuvir. This does not include all of the conceivable combinations of factors. Tell your doctor about any medications you are currently taking as well as any new medications you begin or discontinue using, especially the following: amiodarone; digoxin (digitalis); other drugs to treat hepatitis C, such as simeprevir (Olysio) or sofosbuvir (Sovaldi); rosuvastatin (Crestor); St. John's wort; HIV or AIDS medications such as atazanavir, cobicist This list is not exhaustive; ledipasvir and sofosbuvir may interact with a wide variety of other medications as well. This include both prescription and over-the-counter medications, in addition to herbal and vitamin supplements. Provide any healthcare practitioner who is treating you with a list of all the medications you are currently taking.