Cardiovascular DiseasesLetairis (Generic)
Generic drugs, marketed without brand names, contain the exact same active ingredients used in their brand-name counterparts, but cost significantly less. The drugs are required to meet US Food and Drug Administration (FDA) standards for safety, purity and effectiveness.
Letairis
Ambrisentan reduces the blood pressure found in the lungs, making it easier for the heart to pump blood throughout the body. Ambrisentan is a medication that is prescribed to persons who have been diagnosed with pulmonary arterial hypertension (PAH). Your capacity for exercise will increase, and the progression of your disease will be halted as a result. In rare cases, the medication known as tadalafil is used with ambrisentan (Adcirca).
Ambrisentan tablets
What exactly is ambrisentan?
Ambrisentan lowers the amount of blood pressure in your lungs, making it easier for your heart to pump blood.
Ambrisentan is used to treat high blood pressure in the arteries of the lungs in adults. It makes it easier for you to work out and stops your condition from getting worse. Ambrisentan is sometimes taken along with tadalafil (Adcirca).
For women, the only way to get ambrisentan is through a special program at a certified pharmacy. You have to sign up for the program and agree to use birth control and have blood and pregnancy tests.
Ambrisentan can also be used for other things that aren't in this guide.
Warnings
If you are pregnant or think you might be pregnant, you shouldn't use. Before, during, and after treatment with ambrisentan, you will need to take a pregnancy test. Use a birth control method that is very effective while you are taking ambrisentan and for at least 30 days after your last dose.
If you have pulmonary fibrosis for no known reason, you shouldn't use ambrisentan.
Before you take this drug,
If you are allergic to ambrisentan or have idiopathic pulmonary fibrosis, you shouldn't use it (IPF).
If you are pregnant or think you might be pregnant, don't use ambrisentan. This medicine can cause birth defects that are very bad. If you don't get your period or think you might be pregnant, you should talk to your doctor right away.
Before you can start this treatment, you will need to make sure that you are not pregnant. You will be tested again once a month while you are getting treatment and once a month after you finish your last dose.
Even if you don't want to get pregnant, you can if you have reached puberty (even if you haven't started your periods yet), have never had a hysterectomy or your ovaries removed, or haven't gone through menopause (you have never gone 12 months in a row without a menstrual period).
You must use a highly effective birth control method or two methods together while taking ambrisentan and for at least 30 days after your last dose.
Recommended birth control methods include a tubal ligation, a copper intrauterine device (IUD), or a progesterone implant; one hormone form (birth control pill, skin patch, implant, vaginal ring, or injection) plus one barrier form (condom, diaphragm with spermicide, or cervical cap with spermicide); a condom and a female barrier form (diaphragm with spermicide, or cervical cap with sperm
How do I take the drug ambrisentan?
Follow all of the directions on the label of your prescription, and read any guides or instruction sheets that come with it. Your doctor may change your dose from time to time. Follow the directions to the letter.
Take the medicine every day at the same time, whether you are eating or not.
Do not crush, chew, or break the tablet. Instead, swallow it whole.
You will need medical tests often.
Keep ambrisentan at room temperature, in its original container, away from moisture and heat.
What will happen if I don't take a dose?
Take the medicine as soon as you can, but skip the dose you missed if your next dose is almost due. Take only one dose at a time.
What should I stay away from while I'm on ambrisentan?
Follow your doctor's advice about what you can and cannot eat, drink, or do.
Ambrisentan side effects
If you have hives, trouble breathing, or swelling in your face, lips, tongue, or throat, you may be having an allergic reaction.
Ambrisentan may cause serious side effects. Call your doctor right away if:
Severe shortness of breath, wheezing, cough with foamy mucus, chest pain, swelling, tiredness, rapid weight gain, and low red blood cells (anemia)
�pale skin, unusual tiredness, feeling dizzy or short of breath, cold hands and feet, or liver problems.
�loss of appetite, pain in the upper right side of the stomach, nausea, vomiting, fever, hives, dark urine, stools that look like clay, and jaundice (yellowing of the skin or eyes).
Some common side effects of ambrisentan include swelling in your hands, legs, ankles, or feet; a stuffy nose or pain in your sinuses; or hot flashes or redness in your face.
What effects will other drugs have on ambrisentan?
Tell your doctor about all the other medicines you take, especially cyclosporine.
This list doesn't have everything. Other drugs, such as prescription and over-the-counter drugs, vitamins, and herbal products, may have an effect on ambrisentan. Not every drug interaction that could happen is on this list.
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