our products
Contact phone

Pradaxa

Cardiovascular Diseases Pradaxa (Generic) Generic drugs, marketed without brand names, contain the exact same active ingredients used in their brand-name counterparts, but cost significantly less. The drugs are required to meet US Food and Drug Administration (FDA) standards for safety, purity and effectiveness.
Pradaxa

Blood clots can be avoided with the aid of the medication Pradaxa, which stops the platelets in your blood from sticking together and forming clumps. People who have a certain sort of heart rhythm disorder can take pradaxa to lower their chance of having a stroke and to prevent blood clots from forming in their bodies. Pradaxa can also be used to treat or prevent blood clots in the veins of your legs (a condition known as deep vein thrombosis, or DVT), as well as the veins in your lungs (a condition known as pulmonary embolism, or PE) (pulmonary embolism, or PE).

BEST DEAL!

Save 20% with

Coupon "PKVCbYFj9G"

Product Options

Qty Price Per pill Savings
10 tablet $ 89.95

Best Deal

$ 9.00
Sold out
20 tablet $ 159.95

Best Deal

$ 8.00 $ 19.95
Sold out
30 tablet $ 224.95

Best Deal

$ 7.50 $ 44.90
Sold out
60 tablet $ 419.95

Best Deal

$ 7.00 $ 119.75
Sold out
90 tablet $ 584.95

Best Deal

$ 6.50 $ 224.60
Sold out

The Comprehensive Guide to Generic Pradaxa (Dabigatran): A Novel Oral Anticoagulant for Preventing Blood Clots

Pradaxa, known generically as dabigatran, is a direct thrombin inhibitor and novel oral anticoagulant (NOAC) used to prevent and treat blood clots. It is commonly prescribed for conditions such as atrial fibrillation (AFib), deep vein thrombosis (DVT), and pulmonary embolism (PE). With the availability of generic Pradaxa, this life-saving medication has become more affordable and accessible, benefiting patients worldwide. In this extensive guide, we will explore the science behind dabigatran, its therapeutic applications, benefits, side effects, and the role of generic versions in modern medicine.


What is Pradaxa (Dabigatran)?

Pradaxa (dabigatran) is an oral anticoagulant that works by directly inhibiting thrombin, a key enzyme in the blood clotting process. Unlike traditional anticoagulants like warfarin, dabigatran does not require frequent blood monitoring or dietary restrictions, making it a convenient option for patients. It is available in capsule form and is typically taken once or twice daily, depending on the condition being treated.

Dabigatran is primarily prescribed for:

  1. Atrial Fibrillation (AFib): To reduce the risk of stroke and systemic embolism in patients with non-valvular AFib.

  2. Deep Vein Thrombosis (DVT): To treat and prevent DVT, a condition where blood clots form in the deep veins, usually in the legs.

  3. Pulmonary Embolism (PE): To treat and prevent PE, a condition where blood clots travel to the lungs.

  4. Post-Surgical Thromboprophylaxis: To prevent blood clots after hip or knee replacement surgery.


What is Generic Pradaxa?

Generic Pradaxa refers to the bioequivalent versions of the brand-name medication, containing the same active ingredient (dabigatran etexilate) in the same dosage. These generic versions are produced by pharmaceutical companies other than the original manufacturer and are typically sold at a lower cost. The availability of generic dabigatran has made this life-saving treatment more accessible to patients, particularly in low- and middle-income countries.


Mechanism of Action: How Does Dabigatran Work?

Dabigatran's therapeutic effects are attributed to its ability to directly inhibit thrombin, a critical enzyme in the blood clotting cascade. Here’s a detailed breakdown of its mechanism of action:

  1. Thrombin Inhibition: Dabigatran binds directly to thrombin, preventing it from converting fibrinogen into fibrin, the protein that forms the mesh of blood clots.

  2. Prevention of Clot Formation: By inhibiting thrombin, dabigatran prevents the formation of blood clots, reducing the risk of stroke, DVT, and PE.

  3. Anticoagulant Effects: Dabigatran's anticoagulant effects are predictable and do not require frequent monitoring, unlike warfarin.

  4. Rapid Onset and Offset: Dabigatran has a rapid onset of action (within 1-2 hours) and a relatively short half-life (12-14 hours), allowing for flexible dosing.


Therapeutic Applications of Dabigatran

Dabigatran is used to treat and prevent a variety of conditions related to blood clots, including:

1. Atrial Fibrillation (AFib)

  • Dabigatran is used to reduce the risk of stroke and systemic embolism in patients with non-valvular AFib, a condition characterized by irregular heartbeats.

2. Deep Vein Thrombosis (DVT)

  • It is used to treat and prevent DVT, a condition where blood clots form in the deep veins, usually in the legs.

3. Pulmonary Embolism (PE)

  • Dabigatran is used to treat and prevent PE, a life-threatening condition where blood clots travel to the lungs.

4. Post-Surgical Thromboprophylaxis

  • It is prescribed to prevent blood clots after hip or knee replacement surgery.

5. Off-Label Uses

  • Secondary Prevention of DVT/PE: Dabigatran may be used to prevent recurrent DVT or PE in patients who have completed initial treatment with other anticoagulants.

  • Cancer-Associated Thrombosis: It is being studied for its potential to treat blood clots in patients with cancer.


Benefits of Generic Dabigatran

  1. Cost-Effective: Generic dabigatran is significantly more affordable than the brand-name version, making it accessible to a broader population.

  2. Proven Efficacy: Clinical studies have demonstrated its effectiveness in preventing stroke, DVT, and PE.

  3. Convenience: Dabigatran does not require frequent blood monitoring or dietary restrictions, unlike warfarin.

  4. Rapid Onset and Offset: Its predictable pharmacokinetics allow for flexible dosing and rapid reversal if needed.

  5. Reduced Risk of Bleeding: Compared to warfarin, dabigatran has a lower risk of intracranial hemorrhage (bleeding in the brain).


Side Effects and Safety Profile

Dabigatran is generally well-tolerated, but some patients may experience side effects. These can range from mild to severe and may include:

Common Side Effects

  1. Bleeding: The most common side effect is an increased risk of bleeding, including nosebleeds, bruising, and gastrointestinal bleeding.

  2. Gastrointestinal Issues: Nausea, diarrhea, or stomach pain may occur.

  3. Dyspepsia: Some patients may experience indigestion or heartburn.

Serious Side Effects (Rare)

  1. Severe Bleeding: Dabigatran can cause serious bleeding, including intracranial hemorrhage or gastrointestinal bleeding.

  2. Allergic Reactions: Severe allergic reactions, such as rash, itching, or swelling, are rare but require immediate medical attention.

  3. Liver Dysfunction: Rarely, dabigatran can cause liver damage, leading to elevated liver enzymes or jaundice.

Contraindications

  • Hypersensitivity to dabigatran or any of its components.

  • Active pathological bleeding (e.g., peptic ulcer disease, intracranial hemorrhage).

  • Severe kidney or liver impairment.

  • Pregnancy or breastfeeding (unless absolutely necessary and under close medical supervision).


Cost and Accessibility of Generic Dabigatran

The high cost of brand-name Pradaxa has been a barrier for many patients, particularly in developing countries. The availability of generic dabigatran has significantly reduced the cost, making this life-saving treatment more accessible. Generic versions are widely available and are produced by reputable pharmaceutical companies under strict quality control standards.


Future Directions and Research

Research on dabigatran continues to explore its potential in new therapeutic areas and to optimize its use in existing indications. Some areas of focus include:

  1. Cancer-Associated Thrombosis: Investigating the use of dabigatran for preventing and treating blood clots in cancer patients.

  2. Pediatric Use: Studying its safety and efficacy in children with congenital heart disease or other conditions requiring anticoagulation.

  3. Combination Therapies: Exploring the use of dabigatran in combination with other anticoagulants or antiplatelet drugs to enhance its effects.

  4. Reversal Agents: Developing new reversal agents or strategies to manage bleeding complications associated with dabigatran.


Conclusion

Generic Pradaxa (dabigatran) is a highly effective and widely used medication for the prevention and treatment of blood clots. Its ability to directly inhibit thrombin and provide predictable anticoagulation has made it a cornerstone of therapy for conditions such as atrial fibrillation, DVT, and PE. The availability of generic versions has further enhanced its accessibility, ensuring that more individuals can benefit from its therapeutic effects.

While it is generally safe and well-tolerated, patients should be aware of potential side effects, particularly the risk of bleeding. Regular monitoring and adherence to prescribed guidelines are crucial to maximizing its benefits and minimizing risks.

As research continues to uncover new applications and optimize its use, dabigatran will remain a vital tool in the fight against blood clots and thromboembolic disorders. For patients and healthcare providers alike, generic Pradaxa represents hope, healing, and the promise of improved quality of life.

Dabigatran pill What kind of medication is this? DABIGATRAN has a role in reducing the risk of a blood clot developing as a result of platelets in your blood coming into contact with one another. Those who have a certain kind of cardiac rhythm issue can benefit from taking dabigatran because it lowers their chance of having a stroke and prevents blood clots from forming. In addition, dabigatran can be utilized to treat or prevent blood clots in the veins of your legs (a condition known as deep vein thrombosis, or DVT) as well as the veins in your lungs (pulmonary embolism, or PE). Before I start using this medication, what information is important for my physician to have? If you have an allergy to dabigatran, an artificial heart valve, or active bleeding as a result of surgery, an injury, or another reason, you should not use dabigatran. You have kidney disease (especially if you also take dronedarone or ketoconazole); you take certain other medicines that can increase bleeding risk, such as aspirin, clopidogrel (Plavix), heparin, prasugrel, warfarin (Coumadin, Jantoven); you take an NSAID (nonsteroidal anti-inflammatory drug) on a regular basis, sucralfate; you have recently or recurring bleeding in your stomach or If you get a spinal tap or are given spinal anesthesia while taking dabigatran, you run the risk of developing an extremely dangerous blood clot around your spinal cord (epidural). If you have a history of spinal surgery or repeated spinal taps; if you have recently undergone a spinal tap or epidural anesthesia; if you are currently taking an NSAID (such as Advil, Aleve, or Motrin); or if you are taking any other medications to treat or prevent blood clots, you may be at an increased risk of developing this type of blood clot, which has the potential to cause permanent paralysis. Tell your doctor if you have renal illness, a history of stomach ulcers or bleeding, or if you are over the age of 75. This will allow your doctor to determine whether or not dabigatran is safe for you to use. It is unknown whether or not this medication may cause harm to an unborn child if it is used during pregnancy. Inform your physician if you are pregnant or if you want to become pregnant in the near future. It is unknown whether dabigatran is excreted into breast milk or whether it might cause damage to a baby who is being breastfed. If you are breastfeeding a child, you should let your doctor know about it. What is the correct way to take this medication? Always make sure to follow all of the instructions on the label of your medication. Do not use this medication in greater or lower doses than indicated, nor for a longer period of time than specified. Always remember to take your medication with a full glass of water. You can take dabigatran with or without food depending on your preference. It is important not to chew, break, crush, or otherwise open a dabigatran capsule. Take the tablet in its whole. Because dabigatran prevents your blood from coagulating (clotting) in order to prevent unwanted blood clots, this medicine can also make it easier for you to bleed, even from a minor injury such as falling or bumping your head. This is because dabigatran prevents your blood from clotting in order to prevent unwanted blood clots. If you have any bleeding that will not stop, call your doctor or go to the nearest emergency room if you have fallen, hit your head, or are experiencing any other type of injury. If you have taken dabigatran within the previous 12 hours and are scheduled for any sort of medical test or treatment, including surgery, dental work, or any other type of medical test or treatment, make sure to inform the doctor or dentist in advance. Before undergoing surgery or any other type of medical treatment, it is possible that you will be required to temporarily stop taking dabigatran. You should never stop taking dabigatran without first seeing your physician. When you stop using the medicine, your chance of having a stroke goes up. In the case that you are unable to continue taking dabigatran, your physician may suggest that you switch to a different anticoagulant prescription. Before beginning and periodically while you are receiving therapy with dabigatran, your kidney function may be evaluated using blood tests. Maintain the capsules in their original packaging, whether that is the container or the blister pack. It is imperative that dabigatran capsules not be placed in a daily pill box or any other type of pill organizer. Do not open more than one bottle of this medicine at a time if you have been given a supply of more than 30 days' worth of it at once. Do not start a new bottle until all of the capsules in the previous container have been consumed. Keep at room temperature and away from heat and moisture when storing. Retain each capsule in its respective bottle or blister pack until it is time for you to take the medication. While not in use, ensure that the cap is securely fastened on the bottle. If it has been more than four months since you first opened the container, you should throw away any capsules that have not been used. When the date printed on the blister pack's label as the expiration date has passed, the capsules contained within the pack should be discarded. What should I do if I forget a dose? If it has been less than six hours since you were supposed to take your medication, go ahead and administer the missing dosage as soon as you recall it. If it is almost time for your next scheduled dosage, you should skip the dose that you missed. It is not necessary to take additional medication in order to make up for a missed dosage. For optimal protection against stroke, you should take all of your scheduled doses of dabigatran. What other substances could react with this medication? Before you take dabigatran, tell your doctor if you are also taking rifampin (Rifater, Rifamate, Rimactane, Rifadin). In fact, you should tell your doctor about all of your current medicines and any you start or stop using, particularly other medicines used to treat or prevent blood clots, such as: abciximab, clopidogrel, dipyridamole, eptifibatide, tic This list does not contain everything. There is a possibility that dabigatran will interact negatively with other medications, such as prescription and over-the-counter pharmaceuticals, vitamins, and herbal treatments. This drug guide does not provide a description of all potentially harmful interactions. What side effects should I be on the lookout for when using this medication? If you have an artificial heart valve or if you have any current bleeding as a result of surgery, an injury, or any other reason, you should not take dabigatran. Because dabigatran prevents your blood from coagulating (clotting) in order to prevent unwanted blood clots, this medicine can also make it easier for you to bleed, even from a minor injury such as falling or bumping your head. This is because dabigatran prevents your blood from clotting in order to prevent unwanted blood clots. Steer clear of any actions that can raise your chances of getting cut or bleeding out. If you have bleeding that won't stop, either consult your primary care physician or go to the nearest hospital emergency room. If you have a genetic spinal defect, if you have a spinal catheter in place, if you have a history of spinal surgery or repeated spinal taps, or if you are also using other drugs that can affect blood clotting, then receiving a spinal tap or receiving spinal anesthesia (epidural) while taking dabigatran can cause a very serious blood clot around your spinal cord. This is especially true if you also take other medications that can affect blood clotting. This particular blood clot can result in paralysis that is either temporary or permanent. If you are experiencing back discomfort, tingling or muscular weakness in your lower body, loss of bladder or bowel control, or any other symptoms consistent with a spinal cord blood clot, you should seek immediate medical attention. You should never stop taking dabigatran without first seeing your physician. When you stop using the medicine, your chance of having a stroke goes up. What potential negative reactions may I have to this medication? You should seek immediate medical attention if you experience any of the following symptoms of an allergic reaction: hives; chest discomfort or tightness; wheezing; difficulty breathing; swelling of the cheeks, lips, tongue, or neck; anaphylaxis. If you are experiencing back discomfort, numbness or muscular weakness in your lower body, or loss of bladder or bowel control, you should also seek emergency medical assistance as soon as possible. If you have any bleeding that will not stop, a headache, weakness, dizziness, or the feeling like you might pass out; easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin; blood in your urine or stools; black or tarry stools; coughing up blood or vomiting that looks like coffee grounds; pink or brown urine; joint pain or swelling; or heavy menstrual bleeding, you should contact your doctor as soon as possible. Stomach pain or discomfort, indigestion, or heartburn are examples of common adverse effects that might occur. This list of potential adverse effects is not exhaustive; additional symptoms may also surface. Where exactly may I store my medication? Keep at room temperature and away from heat and moisture when storing. Retain each capsule in its respective bottle or blister pack until it is time for you to take the medication. While not in use, ensure that the cap is securely fastened on the bottle.

Testimonials

high quality medications

Free discreet shipping

Secure online transactions

Money-back guarantee

Fast worldwide delivery

By staying on our site you automatically agree with the storage and processing of your personal data, in accordance with our Privacy Policy.