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Molnupiravir

Antivirals Molnupiravir (Generic) Generic drugs, marketed without brand names, contain the exact same active ingredients used in their brand-name counterparts, but cost significantly less. The drugs are required to meet US Food and Drug Administration (FDA) standards for safety, purity and effectiveness.
Molnupiravir

Molnupiravir is an investigational drug that is currently being researched as a potential therapy for patients with mild to moderate COVID-19. This medication is currently in the process of being researched, therefore not all of its potential side effects have been identified.

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Molnupiravir capsules

What is molnupiravir?

Molnupiravir is an experimental medicine being studied for the treatment of mild-to-moderate COVID-19. This drug is still being studied and all of its risks are not yet known.
The US Food and Drug Administration (FDA) has authorized emergency use of molnupiravir for the treatment of mild-to-moderate COVID-19 in people 18 years of age and older:

  • testing positive for COVID-19;
  • who are at high risk for progression to severe COVID-19, including hospitalization or death; and
  • for whom other COVID-19 treatment options are not available or applicable.

Molnupiravir is not authorized for use:

  • for initiation of treatment in people needing hospitalization due to COVID-19;
  • for prevention before or after exposure of COVID-19; or
  • longer than 5 consecutive days.

Warnings

The US Food and Drug Administration (FDA) has authorized emergency use of molnupiravir for the treatment of mild-to-moderate COVID-19 in people 18 years of age and older.

Before taking this medicine

Tell your doctor if you have any serious or chronic disease.
Molnupiravir may harm an unborn baby if the mother or father is using this medicine:

  • If you are a woman, do not use molnupiravir if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 4 days after your last dose.
  • If you are a man, use an effective birth control if your sex partner is pregnant or is able to get pregnant. Keep using birth control for at least 3 months after your last dose.

Tell your doctor right away if a pregnancy occurs while either the mother or the father is using molnupiravir.
You may need to have a negative pregnancy test before starting this treatment.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of molnupiravir on the baby.
Do not breastfeed while using this medicine, and for at least 4 days after your last dose. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.
Not approved for use by anyone younger than 18 years old.

How should I take molnupiravir?

Take molnupiravir exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Take molnupiravir (four capsules) every 12 hours for 5 consecutive days.
Take this medicine as soon as possible after diagnosis of COVID-19 and within 5 days of when symptoms first appear.
You may take molnupiravir with or without food.
Swallow the capsule whole and do not crush, chew, break, or open it.
Being treated with molnupiravir will not make you less contagious to other people. Keep using infection control methods such as self-isolation, social distancing, hand-washing, using protective face covering, disinfecting surfaces you touch a lot, and not sharing personal items with others.
Molnupiravir is still being studied and all of the risks are not yet known.

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if you are more than 10 hours late for the dose. Do not use two doses at one time.

Molnupiravir side effects

Get emergency medical help if you have signs of an allergic reaction to molnupiravir: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor if you have any new or worsening symptoms.
Common molnupiravir side effects may include:

  • diarrhea, nausea; or
  • dizziness.

What other drugs will affect molnupiravir?

Other drugs may affect molnupiravir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

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