Antivirals, HIV Natdac (Generic) Generic drugs, marketed without brand names, contain the exact same active ingredients used in their brand-name counterparts, but cost significantly less. The drugs are required to meet US Food and Drug Administration (FDA) standards for safety, purity and effectiveness.
Natdac® is an inhibitor of the viral protein NS5A, which is employed in the reproduction of the hepatitis C virus within the liver cells (hepatocytes). As a result, the virus is prevented from entering infected hepatocytes and entering the bloodstream. It is now feasible, as a result of taking this measure, to stop the virus from spreading throughout the body. Natdac® (daclatasvir) is a highly selective direct action drug against the hepatitis C virus (HCV), and it demonstrates no notable activity against other RNA and DNA containing viruses, including the human immunodeficiency virus (HIV) (HIV). Natdac® is an inhibitor of the nonstructural protein 5A (NS5A), which is a multifunctional protein essential for HCV replication. As an inhibitor of NS5A, Natdac® reduces viral RNA replication as well as virion assembly, which are both stages of the life cycle of the virus.
Daclatasvir pill What kind of medication is this? DACLATASVIR is an antiviral medication that stops the hepatitis C virus (HCV) from replicating in your body by inhibiting its replication. Daclatasvir is a medication that is prescribed to persons who have genotype 3 chronic hepatitis C but do not have cirrhosis. This medication is typically administered in conjunction with another medication known as sofosbuvir. In addition to the uses that are described in this pharmaceutical guide, daclatasvir may also be utilized for other purposes. What is the most crucial piece of information I need to be aware of concerning daclatasvir? When other medications are used at the same time as daclatasvir, the potential for dangerous drug interactions exists. Inform all of your healthcare providers about any medications you are now taking, as well as any medications you begin or discontinue taking in the future. Before I start taking daclatasvir, what questions should I ask my doctor or other healthcare provider? If you have an allergy to daclatasvir, you should not take the medication. If you are currently receiving treatment with daclatasvir and sofosbuvir, there may be additional factors contributing to why you should not continue receiving this combination therapy. Talk to your primary care physician about all of your health concerns. It is possible for certain medications to have an adverse reaction when combined with daclatasvir, thus it is important to avoid doing so. If you take any of the following medications, your doctor may need to make adjustments to the treatment plan he or she has devised for you: rifampin; the herb St. John's wort; or medication to treat seizures, such as carbamazepine or phenytoin. Tell your doctor if you have any liver issues other than hepatitis C; heart disease; if you also use amiodarone (a heart rhythm drug); or if you have ever gotten a liver transplant. This will allow your doctor to determine whether or not daclatasvir is safe for you to use. It is unknown whether or not this medication may cause harm to an unborn child if it is used during pregnancy. Inform your physician if you are pregnant or if you want to become pregnant in the near future. It is unknown whether daclatasvir goes into breast milk or whether it might cause damage to a baby who is being breastfed. If you are breastfeeding a child, you should let your doctor know about it. It is not permissible for anyone less than 18 years old to use the medication daclatasvir. What is the recommended dosage of daclatasvir? In most cases, the treatment with daclatasvir lasts for a full year. Always make sure to follow all of the instructions on the label of your medication. Do not use this medication in greater or lower doses than indicated, nor for a longer period of time than specified. It is not recommended to use daclatasvir on its own; rather, it should be administered in conjunction with sofosbuvir. You can take daclatasvir with or without food according on your preference. Combinations of medications are frequently used in the treatment of hepatitis C. Always follow your physician's instructions while using any medicine. You should go through and read all of the patient information, prescription guidelines, and instruction sheets that have been sent to you. Consult your doctor or pharmacist if you have any queries. Do not stop taking any of your hepatitis C medications unless specifically instructed to do so by your doctor. Do not alter your doses or the schedule at which you take your medications without first consulting your doctor. Any individual who has chronic hepatitis C should continue to receive treatment from a medical professional. When you are taking this medication, your liver function will need to be checked on a regular basis by blood testing. Keep at room temperature and away from heat and moisture when storing. What can I expect if I forget to take a dose? When you realize you missed a dosage, take it as soon as you can. If it is almost time for your next scheduled dosage, you should skip the dose that you missed. It is not necessary to take additional medication in order to make up for a missed dosage. What happens if I overdose? Immediately seek out the assistance of a qualified medical professional or dial the Poison Help line at 1-800-222-1222. What should I try to steer clear of while I'm on daclatasvir? If you want to avoid transmitting hepatitis C to other people, using daclatasvir is not going to help. Do not engage in unprotected sexual activity, nor should you share utensils such as razors or toothbrushes. Have a conversation with your healthcare provider about effective methods of preventing the spread of HCV through sexual activity. It is never safe, even for a healthy individual, to share needles that have been used for drugs or medicine. Daclatasvir side effects You should seek immediate medical attention if you have the following symptoms of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or neck. If you take daclatasvir along with sofosbuvir and you also take a prescription called amiodarone for your heart rhythm, this combination of medications has the potential to have adverse effects on your heart that might be life-threatening. If you take these medications and have any of the following symptoms while taking them, you should seek immediate medical attention: chest discomfort; shortness of breath; lightheadedness; or a sensation that you could pass out. If you have significant adverse effects while taking daclatasvir, such as disorientation, problems with memory, extreme dizziness, weakness, exhaustion, or a general sensation of illness, you should contact your doctor as soon as possible. Headaches, feelings of weakness or fatigue are examples of common adverse effects that may occur. This list of potential adverse effects is not exhaustive; additional symptoms may also surface. Make an appointment with your primary care physician to discuss any adverse effects. You can call the FDA at 1-800-FDA-1088 to report any adverse effects. Details on the administration of daclatasvir The typical adult dose for chronic hepatitis C is 60 milligrams to be taken orally once day for a period of 12 weeks. Comments: -Sustained virologic response rates decreased in HCV genotype 3-infected patients with cirrhosis who used this medicine in combination with sofosbuvir for a period of 12 weeks; the appropriate length of treatment for individuals with cirrhosis has not been determined. It is recommended that the product information provided by the manufacturer of sofosbuvir be examined. In individuals with persistent HCV infection of genotype 3, when used in conjunction with sofosbuvir for treatment of the virus. What other medications might potentially interact with daclatasvir? It is possible that your doctor will need to change the dosage of any other medications you take on a routine basis if you begin taking daclatasvir or if you stop using it. There are several medicines that have the potential to interact with daclatasvir, and certain drugs should never be used together. This include both prescription and over-the-counter medications, in addition to herbal and vitamin supplements. This drug guide does not provide a description of all potentially harmful interactions. Talk to your primary care physician about any and all medications you use, including those that you begin or discontinue taking while receiving treatment with daclatasvir. Provide any healthcare practitioner who is treating you with a list of all the medications you are currently taking. To review, keep this drug and all others out of the reach of children at all times, never give anyone else your medications, and make sure you use this medication solely for the purpose for which it was intended.
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